The National Institute on Disability and Rehabilitation Research  has awarded $3 million to the Texas Institute for Rehabilitation and Research Memorial Hermann hospital to perform a 5-year study to determine whether the medicine donepezil is an effective treatment for memory deficits resulting from traumatic brain injury,according to a news release

 The announcement continues: “Memory deficits are among the most common chronic and functionally important consequences of TBI. Donepezil is in a class of medications called acetylcholinesterase inhibitors. Itimproves memory performance in adults with neurological conditions by increasing the amount of the neurotransmitter acetylcholine in the brain. Entitled “Multicenter Evaluation of Memory Remediation after TBI with Donepezil” (the MEMRI-TBI-D Study), this 10-week trial will study the effects of donepezil 10 mg daily on verbal memory problems among adults with TBI in the subacute or chronic recovery period.

“The Brain Injury Research center at TIRR was founded in the 1980s and conducts research that improves outcomes for persons with brain injuries. The principal goal of this research is to reduce barriers to everyday function and to enable persons with brain injury to return to full participation in life.

Dr. David Arciniega, the project director,  said, “The goal of this study is to use donepezil, a medicine that addresses one of the chronic neurochemical deficits produced by traumatic brain injury (tbi), to improve memory performance in persons with TBI. If this treatment is successful, persons with memory problems after TBI will experience improvements in day-to-day memory and be able to participate more fully and independently at home and in the community.”

(Courtesy of

The Orthopedic & Brain Injury Law Group of Goldblatt & Associates, P.C. represents the legal
interests of those individuals who have sustained traumatic orthopedic and brain injuries
due to the negligence of others. In representing our clients, the firm oversees and handles
all aspects of insurance issues ranging from ensuring client’s medical bills are paid and
assisting client’s in getting reimbursed for out of pocket expenses, including lost wages.